Oxalyl chloride → 2-Chloro-2-oxoethyl hexanoate

Reaktionsgleichung

[C:1]([CH2:8][C:9]([OH:11])=[O:10])(=O)[CH2:2][CH2:3][CH2:4]CC.[C:12](Cl)(=O)[C:13]([Cl:15])=[O:14]>>[C:9]([O:11][CH2:12][C:13]([Cl:15])=[O:14])(=[O:10])[CH2:8][CH2:1][CH2:2][CH2:3][CH3:4]

Komponenten

Edukt 2

HCID 65578Oxalyl chloride

HCID 1288593-Oxooctanoic acid

Produkt 1

HCID 147665592-Chloro-2-oxoethyl hexanoate

Reaktionsbedingungen

Temperatur: 55 °C

Versuchsvorschrift

8.7 gm (0.05 mole) of hexanoylacetic acid and 12.7 gm (0.10 mole) of oxalyl chloride were mixed together at room temperature. The reaction was heated gradually over one hour at 50-60° C. for about two hours. Excess oxalyl chloride was removed under reduced pressure to yield an oil that exhibits no --OH stretch by IR. Weight was 9.6 gm.

Aufarbeitung

customExcess oxalyl chloride was removed under reduced pressure
customto yield an oil that

Quellen und Nachweise

ORD-Eintrag: ord-66c59644c1aa45b0a34ad3780e11adf1
Quelldatensatz: uspto-grants-1992_02
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US05091560

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