Dimethylformamide → {1-[8-(3-Sulfamoyl-phenylamino)-thiazolo[4,5-h]quinazoline-2-carbonyl]-pyrrolidin-3-yl}-carbamic acid tert-butyl ester
Reaktionsgleichung
[C:37]([CH3:38])([CH3:39])([CH3:40])[O:41][C:42](=[O:43])[NH:44][CH:45]1[CH2:46][NH:47][CH2:48][CH2:49]1.[CH3:50][N:51]([CH3:52])[CH:53]=[O:54].[CH:1]([N:2]([CH:3]([CH3:4])[CH3:5])[CH2:6][CH3:7])([CH3:8])[CH3:9].[S:10]([NH2:11])(=[O:12])(=[O:13])[c:14]1[cH:15][c:16]([NH:20][c:21]2[n:22][c:23]3[c:24]4[c:25]([cH:26][cH:27][c:28]3[cH:29][n:30]2)[n:31][c:32]([C:34](=[O:35])[OH:36])[s:33]4)[cH:17][cH:18][cH:19]1>>[S:10]([NH2:11])(=[O:12])(=[O:13])[c:14]1[cH:15][c:16]([NH:20][c:21]2[n:22][c:23]3[c:24]4[c:25]([cH:26][cH:27][c:28]3[cH:29][n:30]2)[n:31][c:32]([C:34](=[O:36])[N:47]2[CH2:46][CH:45]([NH:44][C:42]([O:41][C:37]([CH3:38])([CH3:39])[CH3:40])=[O:43])[CH2:49][CH2:48]2)[s:33]4)[cH:17][cH:18][cH:19]1Komponenten
5
