Cyclohexyl bromide → {5-[(Cyclohexyl)-(4-fluoro-benzenesulfonyl)-amino]-2-propyl-benzoimidazol-1-yl}-acetic acid tert-butyl ester

Reaktionsgleichung

[CH:1]1(Br)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C([O-])([O-])=O.[K+].[K+].[C:14]([O:18][C:19](=[O:44])[CH2:20][N:21]1[C:25]2[CH:26]=[CH:27][C:28]([NH:30][S:31]([C:34]3[CH:39]=[CH:38][C:37]([F:40])=[CH:36][CH:35]=3)(=[O:33])=[O:32])=[CH:29][C:24]=2[N:23]=[C:22]1[CH2:41][CH2:42][CH3:43])([CH3:17])([CH3:16])[CH3:15]>CC#N.CCOC(C)=O.O>[C:14]([O:18][C:19](=[O:44])[CH2:20][N:21]1[C:25]2[CH:26]=[CH:27][C:28]([N:30]([CH:1]3[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]3)[S:31]([C:34]3[CH:35]=[CH:36][C:37]([F:40])=[CH:38][CH:39]=3)(=[O:32])=[O:33])=[CH:29][C:24]=2[N:23]=[C:22]1[CH2:41][CH2:42][CH3:43])([CH3:17])([CH3:16])[CH3:15]