Methanol → {4-[5-(Cyclopropyl-methyl-amino)-4-methoxy-8,8-dimethyl-5,6,7,8-tetrahydro-naphthalen-2-ylethynyl]-2-fluoro-phenyl}-acetic acid
Reaktionsgleichung
[CH3:1][O:2][C:3]([CH2:4][c:5]1[c:6]([F:32])[cH:7][c:8]([C:11]#[C:12][c:13]2[cH:14][c:15]3[c:20]([c:21]([O:23][CH3:24])[cH:22]2)[CH:19]([N:25]([CH3:26])[CH:27]2[CH2:28][CH2:29]2)[CH2:18][CH2:17][C:16]3([CH3:30])[CH3:31])[cH:9][cH:10]1)=[O:33].[CH3:36][OH:37].[Li+:34].[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1.[OH-:35]>>[O:2]=[C:3]([CH2:4][c:5]1[c:6]([F:32])[cH:7][c:8]([C:11]#[C:12][c:13]2[cH:14][c:15]3[c:20]([c:21]([O:23][CH3:24])[cH:22]2)[CH:19]([N:25]([CH3:26])[CH:27]2[CH2:28][CH2:29]2)[CH2:18][CH2:17][C:16]3([CH3:30])[CH3:31])[cH:9][cH:10]1)[OH:33]
