Carbon Dioxide → N-(1,1-dimethyl-3-dimethylaminobutyl)acrylamide
Reaktionsgleichung
[CH3:1][C:2]([NH:10][C:11](=[O:16])[CH2:12][CH2:13]OC)([CH3:9])[CH2:3][CH:4]([N:6]([CH3:8])[CH3:7])[CH3:5].[OH-].[Na+].C1(C=CC(O)=CC=1)O.C(=O)=O>>[CH3:9][C:2]([NH:10][C:11](=[O:16])[CH:12]=[CH2:13])([CH3:1])[CH2:3][CH:4]([N:6]([CH3:8])[CH3:7])[CH3:5]Komponenten
5
Reaktionsbedingungen
- Temperatur
- 80 °C
Versuchsvorschrift
A mixture of 144.7 parts (0.63 mole) of N-(1,1-dimethyl-3-dimethylaminobutyl)-3-methoxypropionamide, 1 part of solid sodium hydroxide and 1 part of hydroquinone is charged to a reaction flask fitted with a condenser with a Dry Ice-cooled receiver, a stirrer and temperature control means. The pressure in the flask is reduced to less than 5 mm. and the flask is heated to 80°C. Vigorous reaction begins and liquid condenses in the receiver. After about one-half hour, the temperature is increased to 90°C. and this temperature is maintained for 3 hours. The product is distilled and the desired N-(1,1-dimethyl-3-dimethylaminobutyl)acrylamide is obtained at 80°-91°C./ 0.3-0.4 mm. The yield is 109.1 parts, or 87.4% of the theoretical amount, and the nitrogen percentage is the calculated 14.1%.