Dimethylamine → HCID 20570904, Verbindung

HRID 1577500Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1577500
C[O-].[Na+].[CH3:4][CH:5]([C:7]1[CH:11]=[CH:10][O:9][C:8]=1[C:12]([O:14]C)=O)[CH3:6].[CH3:16][NH:17][CH3:18]>CO>[CH3:16][N:17]([CH3:18])[C:12]([C:8]1[O:9][CH:10]=[CH:11][C:7]=1[CH:5]([CH3:6])[CH3:4])=[O:14]

Komponenten

5

Edukt 3

HCID 674DimethylamineHCID 10942334Sodium MethoxideHCID 67355685HCID 67355685, Verbindung

Produkt 1

HCID 20570904HCID 20570904, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

A solution of sodium methoxide (3.3 g) and 3-(1-methylethyl)-2-furancarboxylic acid, methyl ester (14 g) in dry methanol (50 ml) was treated with dimethylamine gas during 2 hours. The solvent was removed in vacuo and the residue was dissolved in diethyl ether (150 ml) and washed with water (100 ml). The ethereal extract was dried over anhydrous sodium sulphate and evaporation of the solvent gave the title compound (12 g) as an oil.

Aufarbeitung

  1. customThe solvent was removed in vacuo
  2. dissolutionthe residue was dissolved in diethyl ether (150 ml)
  3. washwashed with water (100 ml)
  4. extractionThe ethereal extract
  5. dry with materialwas dried over anhydrous sodium sulphate and evaporation of the solvent

Quellen und Nachweise

ORD-Eintrag
ord-48cb1121fc8d471d9d946acb7638b45d
Quelldatensatz
uspto-grants-1981_09
Patentnummer
US04288443

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