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llms.txt · MCP-AnleitungDatenschutz · Nutzungsbedingungen · Supportv1.8.0
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Ammonia → HCID 53955701, Verbindung

HRID 1577998
Notizen
Druckvorschau

Reaktionsgleichung

Reaktionsgleichung von HRID 1577998
C([S:9][CH2:10][CH2:11][C:12]([N:14]1[C@@H:21]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH2:20][CH2:19][C@H:15]1[C:16]([OH:18])=[O:17])=[O:13])(=O)C1C=CC=CC=1.CO.N>O>[SH:9][CH2:10][CH2:11][C:12]([N:14]1[C@@H:21]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH2:20][CH2:19][C@H:15]1[C:16]([OH:18])=[O:17])=[O:13]
KomponentenReaktionsbedingungenVersuchsvorschriftAufarbeitungQuellen und NachweiseNotizen zur Reaktion

Komponenten

5

Edukt 3

HCID 222AmmoniaHCID 887MethanolHCID 12773841HCID 12773841, Verbindung

Produkt 1

HCID 53955701HCID 53955701, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Reaktionsbedingungen

Temperatur
25 °C

Versuchsvorschrift

This product from Example 3 was added to a solution of methanol saturated with ammonia and was stirred at 25° C. for 2 hours. The solvent was evaporated off, leaving a solid which was stirred in water and filtered. The filtrate was extracted five times with diethyl ether and was acidified. The acidified solution was then extracted with methylene chloride, washed with brine, dried over magnesium sulfate and concentrated to a solid. This residue was extracted with hot hexane from which the title compound crystallized, m.p. 61°-64° C.

Aufarbeitung

  1. customThe solvent was evaporated off
  2. customleaving a solid which
  3. filtrationfiltered
  4. extractionThe filtrate was extracted five times with diethyl ether
  5. extractionThe acidified solution was then extracted with methylene chloride
  6. washwashed with brine
  7. dry with materialdried over magnesium sulfate
  8. concentrationconcentrated to a solid
  9. extractionThis residue was extracted with hot hexane from which the title compound
  10. customcrystallized

Quellen und Nachweise

ORD-Eintrag
ord-ae20c55804c9446da79ecf7fc6bf4478
Quelldatensatz
uspto-grants-1981_09
DOI
10.6084/m9.figshare.5104873.v1
Patentnummer
US04290952

Notizen zur Reaktion

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