1-(Cyclopent-1-en-1-yl)-3-methoxybenzene → HCID 20499284, Verbindung

HRID 1578155Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1578155
O.O.O.C([O-])(=[O:6])C.[Na+].[CH3:9][O:10][C:11]1[CH:12]=[C:13]([C:17]2[CH2:21][CH2:20][CH2:19][CH:18]=2)[CH:14]=[CH:15][CH:16]=1>C(OO)(=O)C.ClCCl>[CH3:9][O:10][C:11]1[CH:12]=[C:13]([C:17]23[O:6][CH:21]2[CH2:20][CH2:19][CH2:18]3)[CH:14]=[CH:15][CH:16]=1

Komponenten

5

Edukt 2

HCID 2724811-(Cyclopent-1-en-1-yl)-3-methoxybenzeneHCID 23665404Sodium Acetate Trihydrate

Produkt 1

HCID 20499284HCID 20499284, VerbindungAusbeute 298 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 6344DichloromethaneLösungsmittelHCID 6585Peracetic AcidLösungsmittel

Versuchsvorschrift

A solution of sodium acetate trihydrate (6 g) in peracetic acid (38 ml) was added dropwise to a stirred solution of 1-(3-methoxyphenyl) cyclopentene (33.5 g) in dichloromethane (200 ml), maintaining the temperature in the range 0°-10°. The solution was stirred for 3 hours at room temperature and then washed with 8% aqueous sodium bicarbonate (700 ml) and 8% sodium thiosulphate solution (400 ml). The organic phase was separated, dried and evaporated and the residue was distilled in vacuo to give the title compound as a colourless oil (25 g) b.p. 89°-92° (0.01 mm).

Aufarbeitung

  1. temperaturemaintaining the temperature in the range 0°-10°
  2. washwashed with 8% aqueous sodium bicarbonate (700 ml) and 8% sodium thiosulphate solution (400 ml)
  3. customThe organic phase was separated
  4. customdried
  5. customevaporated
  6. distillationthe residue was distilled in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-0f2e9478bf6445c1baf6d0eec77f9d60
Quelldatensatz
uspto-grants-1981_09
Patentnummer
US04291059

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