Phenothiazine → N-(2-acryloxyethyl)-2,2,4-trimethyldecahydroquinoline

HRID 1578236

Reaktionsgleichung

Reaktionsgleichung von HRID 1578236
[OH:1][CH2:2][CH2:3][N:4]1[CH:13]2[CH:8]([CH2:9][CH2:10][CH2:11][CH2:12]2)[CH:7]([CH2:14]C)[CH2:6][C:5]1([CH2:18]C)[CH2:16]C.C[O:21][C:22](=O)[CH:23]=[CH2:24].C1C2NC3C(=CC=CC=3)SC=2C=CC=1>C(=O)([O-])[O-].[Zn+2].CO>[C:22]([O:1][CH2:2][CH2:3][N:4]1[CH:13]2[CH:8]([CH2:9][CH2:10][CH2:11][CH2:12]2)[CH:7]([CH3:14])[CH2:6][C:5]1([CH3:16])[CH3:18])(=[O:21])[CH:23]=[CH2:24]

Komponenten

6

Edukt 3

HCID 7108PhenothiazineHCID 7294Methyl AcrylateHCID 205682811-(2-Hydroxyethyl)-2,2,4-triethyldecahydroquinoline2×

Produkt 1

HCID 20568277N-(2-acryloxyethyl)-2,2,4-trimethyldecahydroquinoline

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 19005Zinc CarbonateKatalysatorHCID 887MethanolLösungsmittel

Reaktionsbedingungen

Temperatur
87 °C

Versuchsvorschrift

Following the method described in U.S. Pat. No. 3,872,161, the title compound was prepared by reacting 1 mole of 1-(2-hydroxyethyl)-2,2,4-triethyldecahydroquinoline (hereinafter referred to as HETDQ) with 3 moles methylacrylate in the presence of 0.8 gram phenothiazine and 13 grams zinc carbonate. The above mixture was heated to 87° C. in a 1 liter 3-necked flask equipped with a fractionating column. The pot temperature was gradually increased to a maximum of 164° C. while methanol and other lower boiling point liquid fractions were collected. The reaction took four days.

Aufarbeitung

  1. customequipped with a fractionating column
  2. customwere collected

Quellen und Nachweise

ORD-Eintrag
ord-cb8d79e5dd1542a5aac1341e9ec57eef
Quelldatensatz
uspto-grants-1981_09
Patentnummer
US04292237

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