Formaldehyde → HCID 15581945, Verbindung
Reaktionsgleichung
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][C:8]([NH2:10])=[S:9].[CH3:11]O.[NH:13]1[CH2:18][CH2:17][O:16][CH2:15][CH2:14]1.C=O.[CH3:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]>>[O:16]1[CH2:17][CH2:18][N:13]([CH2:11][NH:10][C:8](=[S:9])[CH:7]([C:23]2[CH:22]=[CH:21][CH:26]=[CH:25][CH:24]=2)[C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=2)[CH2:14][CH2:15]1Komponenten
6
Versuchsvorschrift
2-Phenyl-(2-(2-pyridyl)thioacetamide (1.14 g.) is suspended in 20 ml. of methanol. To the suspension is added 0.49 ml. of morpholine and 0.45 ml. of formalin. The mixture is heated on a steam bath until all of the materials are dissolved. The solution is then cooled and hexane is added. Concentrating to dryness and recrystallizing the residue from isopropanol gives N-morpholinomethyl-2-phenyl-2-(2-pyridyl)thioacetamide, m.p. 128°-130°C.