Hydrochloric Acid → HCID 13389105, Verbindung
Reaktionsgleichung
[C:1]1([CH:7]2[CH2:11][N:10]3[CH2:12][CH2:13][CH2:14][C:9]3=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Li]CCCC.[Cl:20]C1C=CC=C(Cl)C=1S[S:29][C:30]1[C:35]([Cl:36])=[CH:34][CH:33]=[CH:32][C:31]=1[Cl:37].Cl>>[ClH:20].[C:1]1([CH:7]2[CH2:11][N:10]3[CH2:12][CH2:13][CH:14]([S:29][C:30]4[C:31]([Cl:37])=[CH:32][CH:33]=[CH:34][C:35]=4[Cl:36])[C:9]3=[N:8]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1Komponenten
5
Versuchsvorschrift
2,5,6,7-Tetrahydro-2-phenyl-3H-pyrrolo[1,2-a]imidazole was reacted with 2 equivalents of n-BuLi and 1 equivalent of 2,6-dichlorophenyldisulfide according to the general procedure A above except that when the reaction mixture was poured into the aq HCl solution, the HCl salt of the desired product precipitated. It was collected, washed well with cold H2O, then Et2O and dried in vacuo; yield 40.7%; m.p. 96°-99°. Neutralization of the acidic filtrate with NaHCO3, followed by extraction with Et2O, yielded an additional amount of the desired product as the free base (39.2%).