Stannous chloride dihydrate → 4-Hydrazino-5,6,7,8-tetrahydro-1-naphthalenecarboxylic acid hydrochloride

HRID 1585749

Reaktionsgleichung

Reaktionsgleichung von HRID 1585749
[N:1]([O-])=O.[Na+].[NH2:5][C:6]1[C:15]2[CH2:14][CH2:13][CH2:12][CH2:11][C:10]=2[C:9]([C:16]([OH:18])=[O:17])=[CH:8][CH:7]=1.O.O.[Cl:21][Sn]Cl>O.Cl>[ClH:21].[NH:5]([C:6]1[C:15]2[CH2:14][CH2:13][CH2:12][CH2:11][C:10]=2[C:9]([C:16]([OH:18])=[O:17])=[CH:8][CH:7]=1)[NH2:1]

Komponenten

6

Edukt 3

HCID 61436Stannous chloride dihydrateHCID 221117984-Amino-5,6,7,8-tetrahydronaphthalene-1-carboxylic acidHCID 23668193Sodium Nitrite

Produkt 1

HCID 702454754-Hydrazino-5,6,7,8-tetrahydro-1-naphthalenecarboxylic acid hydrochlorideAusbeute 73,3 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 313Hydrochloric AcidLösungsmittel2×HCID 962WaterLösungsmittel

Reaktionsbedingungen

Temperatur
-5 °C

Versuchsvorschrift

A solution of 0.26 g of NaNO2 in 1 ml of water is added to a solution, cooled to -5° C., of 0.73 g of 4-amino-5,6,7,8-tetrahydro-1-naphthalenecarboxylic acid in 10 ml of concentrated HCl. After one and a half hours of stirring at -5° C., a solution of 3.4 g of SnCl2.2H2O in 34 ml of concentrated HCl is added at -5° C. The mixture is stirred for 1 hour at RT and filtered, and the product is washed with concentrated HCl and dried under a stream of dry nitrogen to obtain 0.67 g of the expected hydrazine.

Aufarbeitung

  1. stirringThe mixture is stirred for 1 hour at RT
  2. filtrationfiltered
  3. washthe product is washed with concentrated HCl
  4. customdried under a stream of dry nitrogen

Quellen und Nachweise

ORD-Eintrag
ord-90aa564b72d0456fa4fd67a2cf16f57b
Quelldatensatz
uspto-grants-1999_08
Patentnummer
US05939449

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