N-Iodosuccinimide → HCID 178478182, Verbindung

HRID 1586358Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1586358
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:13]=[CH:12][NH:11][N:10]=2)[CH:5]=[C:6]([Cl:8])[CH:7]=1.C1C(=O)N([I:21])C(=O)C1>ClCCl>[I:21][C:13]1[C:9]([C:4]2[CH:3]=[C:2]([Cl:1])[CH:7]=[C:6]([Cl:8])[CH:5]=2)=[N:10][NH:11][CH:12]=1

Komponenten

4

Edukt 2

HCID 120273N-IodosuccinimideHCID 178478180HCID 178478180, Verbindung

Produkt 1

HCID 178478182HCID 178478182, VerbindungAusbeute 59 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

2.13 g (0.01 mol) of 3-(3,5-dichlorophenyl)pyrazole are dissolved, at room temperature and with stirring, in 50 ml of dichloromethane. 2.5 g (0.011 mol) of n-iodosuccinimide are then added and stirring is then continued for 4 days. The reaction mixture is then concentrated, the solid obtained is washed with heptane and boiled in 100 ml of 1N sodium hydroxide. After cooling, the solid is filtered, washed with water and dried to give 2 g (yield 59%, melting point: 170° C.) of 4-iodo-3-(3,5-dichlorophenyl)pyrazole.

Aufarbeitung

  1. concentrationThe reaction mixture is then concentrated
  2. customthe solid obtained
  3. washis washed with heptane
  4. temperatureAfter cooling
  5. filtrationthe solid is filtered
  6. washwashed with water
  7. customdried

Quellen und Nachweise

ORD-Eintrag
ord-a6e693548f194d1cb81482a444275690
Quelldatensatz
uspto-grants-1999_08
Patentnummer
US05945382

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