Sulfuric Acid → Benzenamine, 2-[(1H-benzimidazol-2-ylthio)methyl]-

HRID 1586465Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1586465
[SH:1][C:2]1[NH:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[NH2:11][C:12]1[CH:19]=[CH:18][CH:17]=[CH:16][C:13]=1[CH2:14]O.S(=O)(=O)(O)O.O.C1(N)C=CC=CC=1.C1(N)C=CC=CC=1>C(O)(=O)C>[NH:3]1[C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=[C:2]1[S:1][CH2:14][C:13]1[CH:16]=[CH:17][CH:18]=[CH:19][C:12]=1[NH2:11]

Komponenten

6

Edukt 4

HCID 1118Sulfuric Acid2×HCID 214392-Aminobenzyl alcohol2×HCID 69793239HCID 69793239, VerbindungHCID 178527775HCID 178527775, Verbindung

Produkt 1

HCID 11054238Benzenamine, 2-[(1H-benzimidazol-2-ylthio)methyl]-

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 176Acetic AcidLösungsmittel

Versuchsvorschrift

A mixture of 9.0 g (60 mMol) of 2-mercaptobenzimidazole and 4.9 g (40 mMol) of 2-aminobenzyl alcohol were heated at 84° C. in a mixture of 45 ml of glacial acetic acid and 12.0 g (120 mMol) of sulfuric acid. After two hours an additional 1 g (8 mMol) of 2-aminobenzyl alcohol and 1 g of sulfuric acid were added. After one hour the reaction mixture was cooled and poured into cold benzenamine hemihydrate.

Aufarbeitung

  1. temperatureAfter one hour the reaction mixture was cooled

Quellen und Nachweise

ORD-Eintrag
ord-4f4360a0d1a74c708a6edd237279810f
Quelldatensatz
uspto-grants-1999_08
Patentnummer
US05945425

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