4-Nitrobenzoyl chloride → Ethanone,2-diazo-(4-nitrophenyl)-

HRID 1588047Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1588047
[N+:1](=[CH2:3])=[N-:2].CN(N=O)/C(/N)=N/[N+]([O-])=O.[OH-].[K+].[N+:16]([C:19]1[CH:27]=[CH:26][C:22]([C:23](Cl)=[O:24])=[CH:21][CH:20]=1)([O-:18])=[O:17]>CCOCC>[N+:1](=[CH:3][C:23]([C:22]1[CH:21]=[CH:20][C:19]([N+:16]([O-:18])=[O:17])=[CH:27][CH:26]=1)=[O:24])=[N-:2]

Komponenten

6

Edukt 4

HCID 85024-Nitrobenzoyl chlorideHCID 9550DiazomethaneHCID 14797Potassium HydroxideHCID 95620601-Methyl-2-nitro-1-nitrosoguanidine

Produkt 1

HCID 138152Ethanone,2-diazo-(4-nitrophenyl)-

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel2×

Versuchsvorschrift

The ethereal diazomethane solution [prepared by adding 12.5 g n-methyl-n-nitro-n-nitroso guanidine to potassium hydroxide (50%, 20 ml) and ether (200 ml) at 0°, stirring for 1 hr, and decanting the ether layer; 65% presumed yield] is treated with TEA (7.7 ml) at 0°, then dropwise with p-nitrobenzoyl chloride (10.21 ml) in ether (25 ml). After stirring for 19 hrs, the reaction is filtered through celite and concentrated to give the title compound.

Aufarbeitung

  1. customdecanting the ether layer
  2. custom65% presumed yield]
  3. stirringAfter stirring for 19 hrs
  4. filtrationthe reaction is filtered through celite and
  5. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-ec9c738cda3543fe863edba5cb923f72
Quelldatensatz
uspto-grants-1993_06
Patentnummer
US05220021

Notizen zur Reaktion

Wird geladen…