Propionyl chloride → N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]propanamide
Reaktionsgleichung
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]([CH3:13])[C:11]([C:14]#[N:15])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[C:16](Cl)(=[O:19])[CH2:17][CH3:18]>>[C:14]([C:11]1[N:12]([CH3:13])[C:8]([C:5]2[CH:6]=[CH:7][C:2]([NH:1][C:16](=[O:19])[CH2:17][CH3:18])=[CH:3][CH:4]=2)=[CH:9][CH:10]=1)#[N:15]Komponenten
3
Versuchsvorschrift
The title compound was prepared according to the general procedure for acylation of 5-(4-aminophenyl)-1-methyl-1H-pyrrole-2-carbonitrile using propionyl chloride (48 μL, 0.55 mmol) to provide N-[4-(5-cyano-1-methyl-1H-pyrrol-2-yl)phenyl]propanamide (0.012 g).
Aufarbeitung
- customThe title compound was prepared
Quellen und Nachweise
- ORD-Eintrag
- ord-84afc0fcbdd145f88138f37f0d2892c3
- Quelldatensatz
- uspto-grants-2007_11
- Patentnummer
- US07297713B2
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