HCID 11833645, Verbindung → 2-methyl-2-(naphthalen-2-yl)propanoic acid

HRID 1594684Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1594684
C([O:8][C:9](=[O:23])[C:10]([C:13]1[CH:22]=[CH:21][C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=1)([CH3:12])[CH3:11])C1C=CC=CC=1>C(O)C.[Pd]>[CH3:12][C:10]([C:13]1[CH:22]=[CH:21][C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=1)([CH3:11])[C:9]([OH:23])=[O:8]

Komponenten

4

Edukt 1

HCID 11833645HCID 11833645, Verbindung

Produkt 1

HCID 117905652-methyl-2-(naphthalen-2-yl)propanoic acidAusbeute 100 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

A mixture of 2,2-dimethyl-(2-naphthyl)acetic acid benzyl ester (0.46 g, 1.5 mmol) and 10% Pd/C (0.040 g) in ethanol (5 mL) was hydrogenated at 1 atmosphere for 16 hours. The catalyst was removed by filtration, and the solvent was evaporated to give 2,2-dimethyl-(2-naphthyl)acetic acid (0.33 g, 1.5 mmol. 100%).

Aufarbeitung

  1. customThe catalyst was removed by filtration
  2. customthe solvent was evaporated

Quellen und Nachweise

ORD-Eintrag
ord-94a134e48f9d4fc481ed7e5fb9846cff
Quelldatensatz
uspto-grants-2001_09
Patentnummer
US06284768B1

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