Acetone → HCID 21707621, Verbindung

HRID 1595096Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1595096
[CH3:1][C:2]12[CH2:7][CH:6]1[CH2:5][CH:4]([CH2:8][CH:9]1OCC[O:10]1)[C:3]2([CH3:15])[CH3:14].CC(C)=O.Cl>O>[CH3:1][C:2]12[CH2:7][CH:6]1[CH2:5][CH:4]([CH2:8][CH:9]=[O:10])[C:3]2([CH3:15])[CH3:14]

Komponenten

5

Edukt 3

HCID 180AcetoneHCID 313Hydrochloric AcidHCID 21707623HCID 21707623, Verbindung

Produkt 1

HCID 21707621HCID 21707621, VerbindungAusbeute 79 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

A mixture of 11.0 g (52 mmol) of 2-(1,2,2-trimethylbicyclo[3.1.0]hex-3-ylmethyl)-[1,3]-dioxolane, 80 ml of acetone, 40 ml of water, 1.5 ml of conc. hydrochloric acid and 10 g of silica gel was stirred at reflux for 4 hours. After filtration, the solution was diluted with diethyl ether, washed with water, dried (MgSO4) and evaporated in vacuo. Kugelrohr distillation of the residue gave 6.8 g (79% yield) of (1,2,2-trimethylbicyclo[3.1.0]hex-3-yl)ethanal.

Aufarbeitung

  1. temperatureat reflux for 4 hours
  2. filtrationAfter filtration
  3. additionthe solution was diluted with diethyl ether
  4. washwashed with water
  5. dry with materialdried (MgSO4)
  6. customevaporated in vacuo
  7. distillationKugelrohr distillation of the residue

Quellen und Nachweise

ORD-Eintrag
ord-84f3f574d5f34933a3e1c3d523be6449
Quelldatensatz
uspto-grants-2001_09
Patentnummer
US06284929B1

Notizen zur Reaktion

Wird geladen…