Potassium Hydroxide → 6-(1,4-Dioxa-8-azaspiro[4,5]dec-8-yl)-1,3,5-triazine-2,4-diamine

HRID 1595939Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1595939
[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[N:5]=[C:4](Cl)[N:3]=1.[O:10]1[C:14]2([CH2:19][CH2:18][NH:17][CH2:16][CH2:15]2)[O:13][CH2:12][CH2:11]1.[OH-].[K+]>O1CCOCC1.C(O)C.O>[O:10]1[C:14]2([CH2:19][CH2:18][N:17]([C:4]3[N:3]=[C:2]([NH2:1])[N:7]=[C:6]([NH2:8])[N:5]=3)[CH2:16][CH2:15]2)[O:13][CH2:12][CH2:11]1

Komponenten

7

Edukt 3

HCID 14797Potassium HydroxideHCID 188311,3,5-Triazine-2,4-diamine, 6-chloro-HCID 674351,4-Dioxa-8-azaspiro(4.5)decane

Produkt 1

HCID 98164366-(1,4-Dioxa-8-azaspiro[4,5]dec-8-yl)-1,3,5-triazine-2,4-diamine

Reagenzien, Katalysatoren, Lösungsmittel 3

HCID 702EthanolLösungsmittelHCID 962WaterLösungsmittelHCID 312751,4-DioxaneLösungsmittel

Versuchsvorschrift

A mixture of 2,4-diamino-6-chloro-1,3,5-triazine (2 g, 14 mmol), 1,4-dioxa-8-azaspiro[4.5]decane (3 g, 21 mmol), and KOH (100 mg, 1.8 mmol) in dioxane (10 mL) and ethanol (40 mL) was heated at reflux overnight, diluted with water, and filtered. The precipitate was rinsed with water and dried under vacuum to provide the title compound.

Aufarbeitung

  1. temperaturewas heated
  2. temperatureat reflux overnight
  3. filtrationfiltered
  4. washThe precipitate was rinsed with water
  5. customdried under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-f1655bbaf844497da65eb9f6a2f0e4d7
Quelldatensatz
uspto-grants-2001_09
Patentnummer
US06288228B1

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