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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 15962Erstellt: 26. Oktober 2026

2-Fluoroaniline → Methyl 4-(2-fluorophenylamino)-1-methyl-6-oxo-1,6-dihydropyridazine-3-carboxylate

https://huagongshe.com/reaction/15962

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-FluoroanilineHCID 9584—
EduktMethyl 4-chloro-1-methyl-6-oxo-1,6-dihydropyridazine-3-carboxylateHCID 57886211—
ProduktMethyl 4-(2-fluorophenylamino)-1-methyl-6-oxo-1,6-dihydropyridazine-3-carboxylateHCID 6667439061%

Reaktionsschritte

The title compound was prepared in 61% yield by the procedure as previously described in Example 166 (step H) using methyl 4-chloro-1-methyl-6-oxo-1,6-dihydropyridazine-3-carboxylate (109 mg, 0.54 mmol, prepared as previously described in Example 1 (steps A-G) and 2-fluoroaniline (0.053 mL, 0.54 mmol).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07732616B2
Quelldatensatzuspto-grants-2010_06
ORD IDord-e3d3226b93d840e1a9ed91970ad037b0
Quellennotizuspto-grants-2010_06