N-bromobutanimide → HCID 19611696, Verbindung

HRID 1602379Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1602379
[Cl:1][C:2]1[C:10]2[O:9][CH:8]=[CH:7][C:6]=2[C:5]([CH3:11])=[CH:4][CH:3]=1.[Br:12]N1C(=O)CCC1=O>C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1.C(Cl)(Cl)(Cl)Cl>[Br:12][CH2:11][C:5]1[C:6]2[CH:7]=[CH:8][O:9][C:10]=2[C:2]([Cl:1])=[CH:3][CH:4]=1

Komponenten

5

Edukt 2

HCID 67184N-bromobutanimideHCID 19611698HCID 19611698, Verbindung

Produkt 1

HCID 19611696HCID 19611696, VerbindungAusbeute 51,6 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 7187Benzoyl PeroxideKatalysatorHCID 5943Carbon TetrachlorideLösungsmittel

Versuchsvorschrift

A mixture of 7-chloro-4-methyl-benzofuran (CAS-number 79444-976; 51.9 g), N-bromosuccinimide (61.4 g), benzoyl peroxide (0.52 g) and carbon tetrachloride (1200 ml) was heated under reflux under the illumination of an 80 W flood lamp for 20 h. The mixture was cooled, and filtered and the filtrate evaporated to dryness. The residue was absorbed onto silica and purified by chromatography on silica using ethyl acetate and hexane (1:20) to give the title compound (39.50 g) as a yellow solid.

Aufarbeitung

  1. temperaturewas heated
  2. temperatureunder reflux under the illumination of an 80 W flood lamp for 20 h
  3. temperatureThe mixture was cooled
  4. filtrationfiltered
  5. customthe filtrate evaporated to dryness
  6. customThe residue was absorbed onto silica
  7. custompurified by chromatography on silica

Quellen und Nachweise

ORD-Eintrag
ord-9919571e6aea444d8b4e0ad277d78b28
Quelldatensatz
uspto-grants-1999_11
Patentnummer
US05981572

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