4-Methyl-2-Pentanol → HCID 54535148, Verbindung
Reaktionsgleichung
[CH3:1][CH:2]([CH3:7])[CH2:3][CH:4]([OH:6])[CH3:5].[C:8](Cl)(=[O:12])[C:9]([Cl:11])=[O:10]>>[C:9]([Cl:11])(=[O:10])[C:8]([O:6][CH:4]([CH2:3][CH:2]([CH3:7])[CH3:1])[CH3:5])=[O:12]Komponenten
3
Versuchsvorschrift
In this example the product was prepared in two synthetic steps. In the first step 4-methyl-2-pentanol was reacted with 50% molar excess of oxalyl chloride. Upon completion of the reaction the excess oxalyl chloride was stripped from the product at reduced pressure to produce 4-methyl-2-pentyl chlorooxalate having an assay of 96.2% and in a corrected yield of 88.2%. In the second step 4-methyl-2-pentyl chlorooxalate was reacted with 3-hydroxy-1,1-dimethylbutyl hydroperoxide in the presence of pyridine to yield the product as described below:
Quellen und Nachweise
- ORD-Eintrag
- ord-30253df839914b72b1e82d3f41c3da2c
- Quelldatensatz
- uspto-grants-1999_11
- DOI