Phosphorus pentachloride → HCID 178479351, Verbindung

HRID 1605853Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1605853
[ClH:1].[C:2]([NH:10][CH2:11][C:12]([OH:14])=O)(=[NH:9])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.P(Cl)(Cl)(Cl)(Cl)[Cl:16]>C(Cl)Cl>[ClH:16].[C:2]([NH:10][CH2:11][C:12]([Cl:1])=[O:14])(=[NH:9])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

Komponenten

4

Edukt 2

HCID 24819Phosphorus pentachlorideHCID 178479352HCID 178479352, Verbindung

Produkt 1

HCID 178479351HCID 178479351, VerbindungAusbeute 99 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To benzimidoylaminoacetic acid hydrochloride (2.2 g., 10 m moles) in 40 ml. of dry methylene chloride is added 2.5 g. (12 m moles) of phosphorous pentachloride, and the reaction mixture allowed to stir overnight at room temperature. The product is filtered, washed successively with methylene chloride (50 ml.), chloroform 2 × 75 ml.) and hexane (50 ml.) and dried in vacuo, 2.5 g. (99% yield).

Aufarbeitung

  1. filtrationThe product is filtered
  2. washwashed successively with methylene chloride (50 ml.), chloroform 2 × 75 ml
  3. dry with material) and hexane (50 ml.) and dried in vacuo, 2.5 g

Quellen und Nachweise

ORD-Eintrag
ord-c9a77337131e4eb1bff0f74bf0579fe0
Quelldatensatz
uspto-grants-1976_04
Patentnummer
US03951952

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