Ethyl benzylidenecyanoacetate → Ethyl 2-cyano-3-phenylpropanoate

HRID 1607388

Reaktionsgleichung

Reaktionsgleichung von HRID 1607388
[CH2:1]([O:3][C:4](=[O:15])[C:5]([C:13]#[N:14])=[CH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH3:2]>C1C=CC=CC=1.[Pd]>[CH2:1]([O:3][C:4](=[O:15])[CH:5]([C:13]#[N:14])[CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[CH3:2]

Komponenten

4

Edukt 1

HCID 74845Ethyl benzylidenecyanoacetate

Produkt 1

HCID 228103Ethyl 2-cyano-3-phenylpropanoateAusbeute 92,5 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 241BenzeneLösungsmittel

Versuchsvorschrift

A solution of 4.56 g of the ester obtained in 30 ml of benzene was hydrogenated over 0.45 g of a 10% palladium/charcoal under a hydrogen atmosphere at room temperature for 4 hours. After filtration of the catalyst, the reaction mixture was concentrated under reduced pressure to obtain 4.26 g of 2-cyano-3-phenylpropionic acid ethyl ester as a colorless oil.

Aufarbeitung

  1. filtrationAfter filtration of the catalyst
  2. concentrationthe reaction mixture was concentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-c3f8c538c3994304819a7c2b309f2c97
Quelldatensatz
uspto-grants-1989_09
Patentnummer
US04863904

Verknüpfte Notizen

Wird geladen…