Ethanol → Ethyl 2-hydroxy-2-phenylpropanoate

HRID 1609718

Reaktionsgleichung

Reaktionsgleichung von HRID 1609718
[C:1]1([C:7]([CH3:12])([OH:11])[C:8]([OH:10])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.S(=O)(=O)(O)O.[CH2:18](O)[CH3:19]>CCOCC>[C:1]1([C:7]([CH3:12])([OH:11])[C:8]([O:10][CH2:18][CH3:19])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Komponenten

5

Edukt 3

HCID 702EthanolHCID 1118Sulfuric AcidHCID 1303Atrolactic acid

Produkt 1

HCID 6429709Ethyl 2-hydroxy-2-phenylpropanoate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

(±)-Phenyllactic acid (4.96 g) and 1/2 ml concentrated sulfuric acid in 150 ml absolute ethanol is refluxed for 18 hours. Solvent is stripped, the residue is dissolved in ether, and extracted with saturated sodium bicarbonate solution. The ether is dried, filtered, and stripped to leave (±)-ethyl phenyllactate. NMR (CDCl3): δ1.3 (t, 3H), 3.0 (d of d, 1H), 3.1 (d of d, 1H), 4.2 (q, 2H), 4.4 (d of d, 1H), 7.3 (m, 5H).

Aufarbeitung

  1. extractionextracted with saturated sodium bicarbonate solution
  2. dry with materialThe ether is dried
  3. filtrationfiltered

Quellen und Nachweise

ORD-Eintrag
ord-a2e094f4293f41d5bfddf16caeeec860
Quelldatensatz
uspto-grants-1995_03
Patentnummer
US05401772

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