Glycidyl methacrylate → HCID 86744516, Verbindung

HRID 1613829Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1613829
[H-].[Na+].[C:3]([C:6]1[CH:19]=[CH:18][C:17]2[S:16][C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[NH:9][C:8]=2[CH:7]=1)(=[O:5])[CH3:4].[C:20]([O:25][CH2:26][CH:27]1[O:29][CH2:28]1)(=[O:24])[C:21]([CH3:23])=[CH2:22]>O1CCCC1>[C:20]([O:25][CH2:26][CH:27]([OH:29])[CH2:28][C:7]1[C:8]2[NH:9][C:10]3[C:15](=[CH:14][CH:13]=[CH:12][CH:11]=3)[S:16][C:17]=2[CH:18]=[CH:19][C:6]=1[C:3](=[O:5])[CH3:4])(=[O:24])[C:21]([CH3:23])=[CH2:22]

Komponenten

5

Edukt 3

HCID 7837Glycidyl methacrylateHCID 24758Sodium hydrideHCID 81131Methyl phenothiazin-2-yl ketone

Produkt 1

HCID 86744516HCID 86744516, VerbindungAusbeute 72,3 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel2×

Versuchsvorschrift

0.20 g (0.0086 mol) of sodium hydride was added carefully to a solution of 2-acetylphenothiazine (2 g, 0.0083 mol) in 150 ml tetrahydrofuran under agitation below 5° C. A solution of glycidyl methacrylate (1.88 g, 0.013 mol) in 10 ml tetrahydrofuran was added dropwise to above solution. The reaction was kept at room temperature for 48 hours. After the solvent was removed, the residue was washed with dilute HCl and water. Dried. 2.3 g of product was obtained by recrystallization with ethyl acetate.

Aufarbeitung

  1. customAfter the solvent was removed
  2. washthe residue was washed with dilute HCl and water
  3. customDried

Quellen und Nachweise

ORD-Eintrag
ord-7bb27ed23ed640189b7960d34b21c915
Quelldatensatz
uspto-grants-1993_03
Patentnummer
US05194544

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