Water → N-(2-Benzoyloxyethyl)pyridinium m-Nitrobenzenesulfonate

HRID 1614299

Reaktionsgleichung

Reaktionsgleichung von HRID 1614299
[N+:1]([C:4]1[CH:5]=[C:6]([S:10]([O-:13])(=[O:12])=[O:11])[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2].[Na+].O.[Br-].[C:17]([O:25][CH2:26][CH2:27][N+:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)(=[O:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>C(Cl)Cl>[N+:1]([C:4]1[CH:5]=[C:6]([S:10]([O-:13])(=[O:11])=[O:12])[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2].[C:17]([O:25][CH2:26][CH2:27][N+:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)(=[O:24])[C:18]1[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=1

Komponenten

5

Edukt 3

HCID 962Water2×HCID 31389Sodium 3-nitrobenzenesulfonateHCID 19762119N-(2-benzoyloxyethyl)pyridinium bromide

Produkt 1

HCID 19762115N-(2-Benzoyloxyethyl)pyridinium m-Nitrobenzenesulfonate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

A solution of 11.26 grams (0.05 mol) of sodium m-nitrobenzenesulfonate in 50 milliters of water was added to a solution of 15.41 grams (0.05 mole) of N-(2-benzoyloxyethyl)pyridinium bromide, prepared as described in Example 2, in 50 milliters of water. The resultant solution was treated with methylene chloride resulting in the formation of three layers. The center layer was isolated, treated with ligroine (bp=70°-90° C.) and allowed to stand with spatula scratching of the oil. Crystallization occurred and the solid was collected, washed with ether and recrystallized from acetonitrile. The yield of product was 6.6 grams (30.67% of theory); mp=128°-30° C.

Aufarbeitung

  1. customprepared
  2. customThe center layer was isolated
  3. additiontreated with ligroine (bp=70°-90° C.)
  4. customCrystallization
  5. customthe solid was collected
  6. washwashed with ether
  7. customrecrystallized from acetonitrile

Quellen und Nachweise

ORD-Eintrag
ord-48554c8397df4be8a654698e6caa0b45
Quelldatensatz
uspto-grants-1993_03
Patentnummer
US05196539

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