Chloride → HCID 20095459, Verbindung

HRID 1614573Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1614573
[CH3:1][NH:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([S:10][CH3:11])=[CH:6][CH:5]=1.[C:12](=[O:15])([O-])[O-].[K+].[K+].[Cl-]>CC(C)=O.O>[C:12]([N:2]([CH3:1])[CH2:3][C:4]1[CH:9]=[CH:8][C:7]([S:10][CH3:11])=[CH:6][CH:5]=1)(=[O:15])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

Komponenten

6

Edukt 3

HCID 312ChlorideHCID 11430Potassium CarbonateHCID 2452234N-Methyl-1-[4-(methylsulfanyl)phenyl]methanamine

Produkt 1

HCID 20095459HCID 20095459, VerbindungAusbeute 199,6 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 180AcetoneLösungsmittelHCID 962WaterLösungsmittel2×

Versuchsvorschrift

N-Methyl-N-(4-methylthiobenzyl)amine (4.2 g) and potassium carbonate (5.2 g) are dissolved in a mixture of acetone (20 ml) and water (20 ml), and thereto is added dropwise benzoy chloride (3.7 ml) gradually under ice cooling. After the mixture is stirred at the same temperature for 30 minutes, the reacting mixture is poured into water, and then extracted with dichloromethane. The extract is washed with aqueous sodium chloride solution, and dried over magnesium sulfate. Dichloromethane is distilled off to give N-benzoyl-N-methyl-N-(4-methylthiobenzyl)amine (6.8 g).

Aufarbeitung

  1. extractionextracted with dichloromethane
  2. washThe extract is washed with aqueous sodium chloride solution
  3. dry with materialdried over magnesium sulfate
  4. distillationDichloromethane is distilled off

Quellen und Nachweise

ORD-Eintrag
ord-e693d1bea73b4058a0d5a8ba57e57816
Quelldatensatz
uspto-grants-1993_03
Patentnummer
US05198448

Notizen zur Reaktion

Wird geladen…