Sulfuric Acid → HCID 10654447, Verbindung
Reaktionsgleichung
[CH2:1]([C:4]1([OH:14])[CH2:13][CH2:12][CH2:11][C:6]2(OCC[O:7]2)[CH2:5]1)[CH:2]=[CH2:3].S(=O)(=O)(O)O>O>[CH2:1]([C:4]1([OH:14])[CH2:13][CH2:12][CH2:11][C:6](=[O:7])[CH2:5]1)[CH:2]=[CH2:3]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A mixture of 7-allyl-1,4-dioxa-spiro[4.5]decan-7-ol (12.8 g) and 0.5 M sulfuric acid (13 mL) is stirred at room temperature for 1 h. Water is then added and the resulting mixture is extracted with diethyl ether. The combined extract is washed with water (3×), brine, and dried (MgSO4). The solvent is evaporated and the residue is triturated with diispropyl ether/heptane 1:1 to give the title compound. Yield: 2.7 g (27% of theory); TLC [silicagel, cyclohexane/ethyl acetate 1:1]: rf=0.55; Mass spectrum (ESI+): m/z=155 [M+H]+.