N-Iodosuccinimide → CID 86717264
Reaktionsgleichung
[Cl:1][C:2]1[C:7]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[N:6][N:5]=[C:4]2[NH:14][N:15]=[CH:16][C:3]=12.[I:17]N1C(=O)CCC1=O>C(#N)C>[Cl:1][C:2]1[C:7]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[N:6][N:5]=[C:4]2[NH:14][N:15]=[C:16]([I:17])[C:3]=12Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A suspension of 4-chloro-5-phenyl-1H-pyrazolo[3,4-c]pyridazine (2.44 g, 10.6 mmol) and N-iodosuccinimide (3.58 g, 15.9 mmol) in acetonitrile (106 mL) was heated at reflux for 1 d. The yellow solid was collected by filtration while warm to provide a mixture of the title compound and starting material (9:1, 4 g).
Aufarbeitung
- temperaturewas heated
- temperatureat reflux for 1 d
- filtrationThe yellow solid was collected by filtration
- temperaturewhile warm
- customto provide
Quellen und Nachweise
- ORD-Eintrag
- ord-28c4ad372a27422abded9e768162a965
- Quelldatensatz
- uspto-grants-2014_07
- Patentnummer
- US08765762B2
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