Methanesulfonyl chloride → HCID 19351329, Verbindung
Reaktionsgleichung
[CH3:1][C:2]1[CH2:3][C:4](=[O:14])[N:5]([C:7]2[CH:12]=[CH:11][C:10]([NH2:13])=[CH:9][CH:8]=2)[N:6]=1.[CH3:15][S:16](Cl)(=[O:18])=[O:17]>>[CH3:1][C:2]1[CH2:3][C:4](=[O:14])[N:5]([C:7]2[CH:12]=[CH:11][C:10]([N:13]([S:16]([CH3:15])(=[O:18])=[O:17])[S:16]([CH3:15])(=[O:18])=[O:17])=[CH:9][CH:8]=2)[N:6]=1Komponenten
3
Versuchsvorschrift
From the reaction of 5-methyl-2-(4-aminophenyl)-2,4-dihydro-pyrazol-3-one and methansulfonylchloride (reaction per Example 11, where methanesulfonylchloride is used in respective molecular amounts), N-(4-(4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)-phenyl)-N-methylsulfonylmethanesulfonamide is obtained. Subsequent reaction with 2-ethyl aniline yields N-(4-(4-(2-Ethylanilinomethylene)-4,5-dihydro-3-methyl-5-oxo-1H-pyrazol-1-yl)-phenyl)-N-methylsulfonylmethansulfonamide, Mp: 268° C.
Quellen und Nachweise
- ORD-Eintrag
- ord-c3b57e62fcc646669e2d120ddd54176a
- Quelldatensatz
- uspto-grants-2000_03