Water → 6-bromo-4-diethylthiocarbamoylthio-3-propyl-2H-1-benzopyran-2-one

HRID 1636433

Reaktionsgleichung

Reaktionsgleichung von HRID 1636433
[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[O:10][C:9](=[O:11])[C:8]([CH2:12][CH2:13][CH3:14])=[C:7](Cl)[C:6]=2[CH:16]=1.[CH2:17]([N:19]([CH2:23][CH3:24])[C:20](=[S:22])[S-:21])[CH3:18].[Na+].O>CN(C)C=O>[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[O:10][C:9](=[O:11])[C:8]([CH2:12][CH2:13][CH3:14])=[C:7]([S:22][C:20](=[S:21])[N:19]([CH2:23][CH3:24])[CH2:17][CH3:18])[C:6]=2[CH:16]=1

Komponenten

5

Edukt 3

HCID 962WaterHCID 533728Sodium DiethyldithiocarbamateHCID 193516286-bromo-4-chloro-3-propyl-2H-1-benzopyran-2-one

Produkt 1

HCID 193516196-bromo-4-diethylthiocarbamoylthio-3-propyl-2H-1-benzopyran-2-one

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

A solution of 6-bromo-4-chloro-3-propyl-2H-1-benzopyran-2-one (0.5 g) in dimethylformamide (2 ml) was treated with sodium diethyldithiocarbamate (0.34 g). The mixture was stirred at room temperature under nitrogen overnight and then poured into water, extracted with diethyl ether and the extract washed with brine, dried and evaporated under reduced pressure to give 6-bromo-4-diethylthiocarbamoylthio-3-propyl-2H-1-benzopyran-2-one, m.p. 135-7°. (compound 16)

Aufarbeitung

  1. extractionextracted with diethyl ether
  2. washthe extract washed with brine
  3. customdried
  4. customevaporated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-68208a4527674e13946886f99212d572
Quelldatensatz
uspto-grants-2000_03
Patentnummer
US06034121

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