Water → HCID 66735912, Verbindung

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Reaktionsgleichung

F[C:2]1[CH:3]=[CH:4][C:5]([N+:11]([O-:13])=[O:12])=[C:6]([CH:10]=1)[C:7]([NH2:9])=[O:8].[C:14]1([S:20]([O:22][Na])=[O:21])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.O>CS(C)=O>[C:14]1([S:20]([C:2]2[CH:3]=[CH:4][C:5]([N+:11]([O-:13])=[O:12])=[C:6]([CH:10]=2)[C:7]([NH2:9])=[O:8])(=[O:22])=[O:21])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Komponenten

Reaktionsbedingungen

Temperatur: 50 °C

Versuchsvorschrift

5-Fluoro-2-nitro-benzamide (2.5 g, 13.59 mmol) in DMSO (40 mL) was treated with solid 97% PhSO2Na (2.48 g, 14.95 mmol) and heated at 50° C. (oil bath temperature) for 60 hours. The reaction was added dropwise into 40 mL of iced water. Filtration of the solid afforded 3.55 g (85% yield) of title compound.

Aufarbeitung

filtrationFiltration of the solid

Quellen und Nachweise

ORD-Eintrag: ord-468d228a0acc48849718e2c95a630729
Quelldatensatz: uspto-grants-2012_02
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08114865B2

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