3,5,5-Trimethyl-2-pyrazoline → 1-(2,6-Dichlorophenylsulphonylcarbamoyl)-3,5,5-trimethyl-2-pyrazoline

HRID 1650989Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1650989
[CH3:1][C:2]1[CH2:6][C:5]([CH3:8])([CH3:7])[NH:4][N:3]=1.[Cl:9][C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([Cl:16])[C:11]=1[S:17]([N:20]=[C:21]=[O:22])(=[O:19])=[O:18]>O.C1(C)C=CC=CC=1>[Cl:9][C:10]1[CH:15]=[CH:14][CH:13]=[C:12]([Cl:16])[C:11]=1[S:17]([NH:20][C:21]([N:4]1[C:5]([CH3:8])([CH3:7])[CH2:6][C:2]([CH3:1])=[N:3]1)=[O:22])(=[O:18])=[O:19]

Komponenten

5

Edukt 2

HCID 2314643,5,5-Trimethyl-2-pyrazolineHCID 128751892,6-Dichlorobenzenesulfonyl isocyanate

Produkt 1

HCID 230508981-(2,6-Dichlorophenylsulphonylcarbamoyl)-3,5,5-trimethyl-2-pyrazoline

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 962WaterLösungsmittelHCID 1140TolueneLösungsmittel

Versuchsvorschrift

11.2 g of the 3,5,5-trimethyl-2-pyrazoline obtained according to example I(b) are added dropwise while stirring, cooling in cold water and under a nitrogen blanket to a solution of 25.2 g of the 2,6-dichlorobenzenesulphonylisocyanate obtained according to example I(a) in 200 ml of dry toluene. After stirring at room temperature for two hours, the precipitate is sucked off and washed successively with dry toluene and petroleum ether (40-60). The desired 1-(2,6-dichlorophenylsulphonylcarbamoyl)-3,5,5-trimethyl-2-pyrazoline is obtained in a yield of 20.07 g; melting-point 270° C. (decomposition).

Aufarbeitung

  1. additionare added dropwise
  2. customobtained
  3. stirringAfter stirring at room temperature for two hours
  4. washwashed successively with dry toluene and petroleum ether (40-60)

Quellen und Nachweise

ORD-Eintrag
ord-cf3b4d36ab914790bb87113a3ce05a18
Quelldatensatz
uspto-grants-1990_05
Patentnummer
US04927452

Notizen zur Reaktion

Wird geladen…