Formaldehyde → HCID 14751299, Verbindung

HRID 1651129Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1651129
[CH3:1][C:2]([C:5]1[CH:6]=[C:7]([CH:16]=[CH:17][C:18]=1[OH:19])[C:8]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)=[O:9])([CH3:4])[CH3:3].Cl.[CH3:21][NH:22][CH3:23].[OH-].[Na+].[CH2:26]=O>C(O)C>[CH3:21][N:22]([CH2:26][C:17]1[CH:16]=[C:7]([CH:6]=[C:5]([C:2]([CH3:1])([CH3:3])[CH3:4])[C:18]=1[OH:19])[C:8]([C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1)=[O:9])[CH3:23]

Komponenten

6

Edukt 4

HCID 712FormaldehydeHCID 10473Dimethylamine, hydrochlorideHCID 14798Sodium HydroxideHCID 230514754-Benzoyl-2-tert-butylphenol

Produkt 1

HCID 14751299HCID 14751299, VerbindungAusbeute 68,6 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

3-(1,1-Dimethylethyl)-4-hydroxybenzophenone (2.5 g), 1.71 g of dimethylamine hydrochloride, 0.78 g of sodium hydroxide, and 0.68 g of paraformaldehyde were dissolved in 30 ml of ethanol and the mixture was heated to reflux for 16 hours. The ethanol was then evaporate. Water was added to the residue and the crystals which separated out were filtered and recrystallized from 90% ethanol to give 2.1 g of the desire product, m.p. 129° C.

Aufarbeitung

  1. temperaturethe mixture was heated
  2. temperatureto reflux for 16 hours
  3. customThe ethanol was then evaporate
  4. additionWater was added to the residue
  5. customthe crystals which separated out
  6. filtrationwere filtered
  7. customrecrystallized from 90% ethanol

Quellen und Nachweise

ORD-Eintrag
ord-5eb76259076143588cb276fb41a5f248
Quelldatensatz
uspto-grants-1990_05
Patentnummer
US04927835

Notizen zur Reaktion

Wird geladen…