Potassium thiocyanate → (3-Chloro-2-methylphenyl)thiosemicarbazide

HRID 1654068Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1654068
Cl.[Cl:2][C:3]1[C:4]([CH3:11])=[C:5]([NH:9][NH2:10])[CH:6]=[CH:7][CH:8]=1.[S-:12][C:13]#[N:14].[K+]>C(O)C>[Cl:2][C:3]1[C:4]([CH3:11])=[C:5]([NH:9][NH:10][C:13]([NH2:14])=[S:12])[CH:6]=[CH:7][CH:8]=1

Komponenten

4

Edukt 2

HCID 516872Potassium thiocyanateHCID 12732296(3-Chloro-2-methylphenyl)hydrazine hydrochloride

Produkt 1

HCID 20079518(3-Chloro-2-methylphenyl)thiosemicarbazide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

19.3 g (0.1 mole) of 3-chloro-2-methylphenylhydrazinehydrochloride were dissolved in 200 ml of absolute ethanol. 11.64 g (0.12 mole) of potassium thiocyanate were added to the solution, and the mixture was heated during reflux for 16 hours. The mixture was then cooled, whereby the product was partially precipitated, and the mixture was subsequently evaporated to dryness by means of a rotating evaporator. The product was recrystallized from 200 ml water and 250 ml methanol, separated by filtration and washed thoroughly with water.

Aufarbeitung

  1. temperaturethe mixture was heated
  2. temperatureduring reflux for 16 hours
  3. temperatureThe mixture was then cooled
  4. customwhereby the product was partially precipitated
  5. customthe mixture was subsequently evaporated to dryness by means of a rotating evaporator
  6. customThe product was recrystallized from 200 ml water and 250 ml methanol
  7. customseparated by filtration
  8. washwashed thoroughly with water

Quellen und Nachweise

ORD-Eintrag
ord-b1c751435ff54ea888fe464c8808333d
Quelldatensatz
uspto-grants-1995_04
Patentnummer
US05405857

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