Methanesulfonyl chloride → 1-Propanol, 3-(trimethylsilyl)-

HRID 1655989Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1655989
[CH3:1][S:2](Cl)(=[O:4])=[O:3].[CH3:6][Si:7]([CH3:13])([CH3:12])[CH2:8][CH2:9][CH2:10][OH:11]>ClCCl>[CH3:6][Si:7]([CH3:13])([CH3:12])[CH2:8][CH2:9][CH2:10][OH:11].[CH3:1][S:2]([O-:4])(=[O:11])=[O:3]

Komponenten

5

Edukt 2

HCID 31297Methanesulfonyl chlorideHCID 762131-Propanol, 3-(trimethylsilyl)-

Produkt 2

HCID 762131-Propanol, 3-(trimethylsilyl)-HCID 85257Methanesulfonate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

Methanesulfonylchloride (0.73 ml, 9 mmol) was added dropwise to a solution of 3-(trimethylsilyl)-1-propanol (1.2 ml, 7.56 mmol) cooled at 0° C. in 20 ml of dichloromethane. After 45 minutes stirring, the reaction mixture was partitioned between water and dichloromethane, the organic phase was separated, the solvent was evaporated under reduced pressure to afford the expected 3-(trimethylsilyl)-1-propanol, methanesulfonate in crude quantitative yield.

Aufarbeitung

  1. customthe reaction mixture was partitioned between water and dichloromethane
  2. customthe organic phase was separated
  3. customthe solvent was evaporated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-7b4c312d11d74f4395c712f71157cdbd
Quelldatensatz
uspto-grants-1993_10
Patentnummer
US05252587

Notizen zur Reaktion

Wird geladen…