4-Toluenesulfonyl chloride → HCID 53828981, Verbindung

HRID 1659895Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1659895
[C:1]1([CH3:11])[CH:6]=[CH:5][C:4]([S:7](Cl)(=[O:9])=[O:8])=[CH:3][CH:2]=1.[Cl:12][C:13]1[C:14]([Cl:25])=[CH:15][C:16]2[O:21][CH2:20][CH2:19][C:18](=[N:22][OH:23])[C:17]=2[CH:24]=1>N1C=CC=CC=1>[Cl:12][C:13]1[C:14]([Cl:25])=[CH:15][C:16]2[O:21][CH2:20][CH2:19][C:18](=[N:22][O:23][S:7]([C:4]3[CH:5]=[CH:6][C:1]([CH3:11])=[CH:2][CH:3]=3)(=[O:9])=[O:8])[C:17]=2[CH:24]=1

Komponenten

4

Edukt 2

HCID 73974-Toluenesulfonyl chlorideHCID 857730826,7-Dichloro-2,3-dihydro-4-(hydroxyimino)-4H-1-benzopyran

Produkt 1

HCID 53828981HCID 53828981, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel2×

Versuchsvorschrift

A solution of p-toluenesulfonyl chloride (103 g) in 125 ml pyridine was added dropwise at 5°-10° to 6,7-dichloro-2,3-dihydro-4-(hydroxyimino)-4H-1-benzopyran (62.5 g) in 250 ml pyridine. The reaction mixture was then stirred for 20 hours at room temperature, poured into ice-water to separate out the title compound, which was filtered, washed several times with water, then once with ether, and finally dried in air. Yield: 101.8 g; m.p. 180°-184°.

Aufarbeitung

  1. customto separate out the title compound, which
  2. filtrationwas filtered
  3. washwashed several times with water
  4. dry with materialonce with ether, and finally dried in air

Quellen und Nachweise

ORD-Eintrag
ord-19303a9928b9407aac4fb177cf7d67be
Quelldatensatz
uspto-grants-1981_12
Patentnummer
US04305954

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