Potassium Carbonate → N-biphenyl-4-yl-3-oxo-3-[4-(2-trifluoromethyl-benzyl)-piperazin-1-yl]-propionamide

Reaktionsgleichung

Cl.[C:2]1([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:7]=[CH:6][C:5]([NH:8][C:9](=[O:19])[CH2:10][C:11](=[O:18])[N:12]2[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]2)=[CH:4][CH:3]=1.C([O-])([O-])=O.[K+].[K+].Br[CH2:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][C:35]=1[C:40]([F:43])([F:42])[F:41]>CN(C=O)C.O>[C:2]1([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:3]=[CH:4][C:5]([NH:8][C:9](=[O:19])[CH2:10][C:11](=[O:18])[N:12]2[CH2:13][CH2:14][N:15]([CH2:33][C:34]3[CH:39]=[CH:38][CH:37]=[CH:36][C:35]=3[C:40]([F:41])([F:42])[F:43])[CH2:16][CH2:17]2)=[CH:6][CH:7]=1