Potassium Carbonate → 4-[(3-Chloro-2-fluoro-phenyl)amino]-6-(1,4-dioxa-spiro[4.5]decan-8-yl-oxy)-7-methoxy-quinazoline

Reaktionsgleichung

C(=O)([O-])[O-].[K+].[K+].CS([O:11][CH:12]1[CH2:21][CH2:20][C:15]2([O:19][CH2:18][CH2:17][O:16]2)[CH2:14][CH2:13]1)(=O)=O.[Cl:22][C:23]1[C:24]([F:43])=[C:25]([NH:29][C:30]2[C:39]3[C:34](=[CH:35][C:36]([O:41][CH3:42])=[C:37](O)[CH:38]=3)[N:33]=[CH:32][N:31]=2)[CH:26]=[CH:27][CH:28]=1>CN(C)C=O.O.C(OCC)(=O)C>[Cl:22][C:23]1[C:24]([F:43])=[C:25]([NH:29][C:30]2[C:39]3[C:34](=[CH:35][C:36]([O:41][CH3:42])=[C:37]([O:11][CH:12]4[CH2:21][CH2:20][C:15]5([O:19][CH2:18][CH2:17][O:16]5)[CH2:14][CH2:13]4)[CH:38]=3)[N:33]=[CH:32][N:31]=2)[CH:26]=[CH:27][CH:28]=1