4-Methylmorpholine → 2'-Chloro-5'-(3-cyclohexyl-ureido)-biphenyl-4-carboxylic acid {4-[4-(propane-1-sulfonyl)-piperazin-1-ylmethyl]-phenyl}-amide

Reaktionsgleichung

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]([NH:11][CH:12]2[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13]2)=[O:10])=[CH:4][C:3]=1[C:18]1[CH:23]=[CH:22][C:21]([C:24](O)=[O:25])=[CH:20][CH:19]=1.[CH2:27]([S:30]([N:33]1[CH2:38][CH2:37][N:36]([CH2:39][C:40]2[CH:45]=[CH:44][C:43]([NH2:46])=[CH:42][CH:41]=2)[CH2:35][CH2:34]1)(=[O:32])=[O:31])[CH2:28][CH3:29].CN(C(ON1N=NC2C=CC=CC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.CN1CCOCC1>CN(C=O)C>[CH2:27]([S:30]([N:33]1[CH2:38][CH2:37][N:36]([CH2:39][C:40]2[CH:41]=[CH:42][C:43]([NH:46][C:24]([C:21]3[CH:22]=[CH:23][C:18]([C:3]4[CH:4]=[C:5]([NH:8][C:9]([NH:11][CH:12]5[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17]5)=[O:10])[CH:6]=[CH:7][C:2]=4[Cl:1])=[CH:19][CH:20]=3)=[O:25])=[CH:44][CH:45]=2)[CH2:35][CH2:34]1)(=[O:31])=[O:32])[CH2:28][CH3:29]