Hydrochloric Acid → HCID 12824993, Verbindung

HRID 1679508Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1679508
[Cl:1][CH:2]([CH2:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][C:15]([CH3:23])([CH3:22])[C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[CH:9][CH:8]=1)[C:3]([O-:5])=[O:4].[Na+].Cl>O>[Cl:1][CH:2]([CH2:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][C:15]([CH3:23])([CH3:22])[C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[CH:9][CH:8]=1)[C:3]([OH:5])=[O:4]

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 23695280HCID 23695280, Verbindung

Produkt 1

HCID 12824993HCID 12824993, VerbindungAusbeute 91,4 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

In 5 ml of water is dissolved 350 mg of sodium 2-chloro-3-[4-(2,2-dimethyl-2-phenylethyloxy)phenyl]propionate, followed by the addition of 2-N hydrochloric acid. The oily substance separated out is extracted with ether. The extract is washed with water and the solvent is distilled off. The described procedure gives 300 mg of 2-chloro-3-[4-(2,2-dimethyl-2-phenylethyloxy)phenyl]propionic acid, as a yellow oily substance.

Aufarbeitung

  1. customThe oily substance separated out
  2. extractionis extracted with ether
  3. washThe extract is washed with water
  4. distillationthe solvent is distilled off

Quellen und Nachweise

ORD-Eintrag
ord-bc91a5d96a9d417b8328ab8e47035566
Quelldatensatz
uspto-grants-1978_03
Patentnummer
US04080505

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