Water → 2,3,4,9-Tetrahydro-6-methoxy-1H-carbazol-1-one

HRID 1679824Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1679824
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([NH:9]N=C2CCCCC2=O)=[CH:5][CH:4]=1.[OH2:18].S(=O)(=O)(O)O>C(O)C>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:6](=[CH:7][CH:8]=1)[NH:9][C:4]1[C:5](=[O:18])[CH2:6][CH2:7][CH2:8][C:3]2=1

Komponenten

5

Edukt 3

HCID 962WaterHCID 1118Sulfuric AcidHCID 753926HCID 753926, Verbindung

Produkt 1

HCID 28568112,3,4,9-Tetrahydro-6-methoxy-1H-carbazol-1-one

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

232 g. (1 mole) of cyclohexanedione-mono-p-methoxyphenylhydrazone, 1200 ml. of water, 350 g. of sulfuric acid (65 Be) and 100 ml. of ethanol are allowed to boil under reflux for three hours. After cooling down, the mixture is filtered with suction and rendered free from acid by washing with water. The resultant 6-methoxy-1,2,3,4-tetrahydrocarbazol-1-one melts at 222° C. and gives a yield of 193 g. (=90% of the theoretical).

Aufarbeitung

  1. temperatureunder reflux for three hours
  2. temperatureAfter cooling down
  3. filtrationthe mixture is filtered with suction
  4. washby washing with water

Quellen und Nachweise

ORD-Eintrag
ord-c8c3d8b5a40a47e1b2c19341d86dfc4c
Quelldatensatz
uspto-grants-1981_06
Patentnummer
US04271073

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