Acetic Anhydride → HCID 53964927, Verbindung

HRID 1680270Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1680270
[CH3:1][O:2][C:3]([CH:5]1[C:13]2[C:8](=[CH:9][C:10]([C:15](=[O:22])[C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[C:11]([OH:14])[CH:12]=2)[CH2:7][CH2:6]1)=[O:4].[C:23](OC(=O)C)(=[O:25])[CH3:24]>>[CH3:1][O:2][C:3]([CH:5]1[C:13]2[C:8](=[CH:9][C:10]([C:15](=[O:22])[C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[C:11]([O:14][C:23](=[O:25])[CH3:24])[CH:12]=2)[CH2:7][CH2:6]1)=[O:4]

Komponenten

3

Edukt 2

HCID 7918Acetic AnhydrideHCID 54109752HCID 54109752, Verbindung

Produkt 1

HCID 53964927HCID 53964927, Verbindung

Versuchsvorschrift

A solution of 10 g of 5-benzoyl-6-hydroxy-indane-1-carboxylic acid methyl ester in 100 ml of acetic anhydride is heated to the reflux temperature for 4 hours under anhydrous conditions. It is then evaporated to dryness in vacuo. The evaporation residue is mixed with 200 ml of toluene and evaporated in vacuo. Distillation of the evaporation residue in a high vacuum gives, in the fraction boiling at 195°-200° C./0.06 mm Hg, 5-benzoyl-6-acetoxy-indane-1-carboxylic acid methyl ester in the form of a colourless oil.

Aufarbeitung

  1. customIt is then evaporated to dryness in vacuo
  2. additionThe evaporation residue is mixed with 200 ml of toluene
  3. customevaporated in vacuo
  4. distillationDistillation of the evaporation residue in a high vacuum

Quellen und Nachweise

ORD-Eintrag
ord-835c95af56274dcab7a2930d96b82be7
Quelldatensatz
uspto-grants-1981_06
Patentnummer
US04272547

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