HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Liothyronine → N-Bromoacetyl-3,3',5-triiodothyronine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Liothyronine | HCID 5920 | — |
| Edukt | Bromoacetyl bromide | HCID 61147 | — |
| Lösungsmittel | Ethyl Acetate | HCID 8857 | — |
| Produkt | N-Bromoacetyl-3,3',5-triiodothyronine | HCID 122086 | — |
Reaktionsschritte
According to the present invention a solution of 3,3',5-triiodo-L-thyronine and bromoacetyl bromide in ethyl acetate is refluxed for a period of time to produce the bromoacetylated hormone which is then fractionated by high speed countercurrent chromatography to yield highly pure N-bromoacetyl-3,3',5-triiodo-L-thyronine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05169984 |
| Quelldatensatz | uspto-grants-1992_12 |
| ORD ID | ord-5970f06b834348c39766db5e4bc8499b |
| Quellennotiz | uspto-grants-1992_12 |