Ammonium Hydroxide → 2-{2-[(2-hydroxyethyl)amino]-1H-benzimidazol-1-yl}-1-phenylethanone

HRID 1683716Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1683716
[OH-].[NH4+].Br.Br.[OH:5][CH2:6][CH2:7][NH:8][C:9]1[N:13]([CH2:14][C:15]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[O:16])[C:12]2[CH:23]=[CH:24][CH:25]=[CH:26][C:11]=2[N:10]=1>>[OH:5][CH2:6][CH2:7][NH:8][C:9]1[N:13]([CH2:14][C:15]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[O:16])[C:12]2[CH:23]=[CH:24][CH:25]=[CH:26][C:11]=2[N:10]=1

Komponenten

3

Edukt 2

HCID 14923Ammonium HydroxideHCID 190408002-(2-Hydroxyethylamino)-1-phenacylbenzimidazole dihydrobromide

Produkt 1

HCID 28501002-{2-[(2-hydroxyethyl)amino]-1H-benzimidazol-1-yl}-1-phenylethanone

Versuchsvorschrift

Add 22% ammonium hydroxide to 75 ml of a hot solution of the dihydrobromide obtained in Step A in 95° alcohol until a pH of approximately 10 is obtained. The title compound precipitates and is filtered, washed with water and dried.

Aufarbeitung

  1. customis obtained
  2. customThe title compound precipitates
  3. filtrationis filtered
  4. washwashed with water
  5. customdried

Quellen und Nachweise

ORD-Eintrag
ord-39c6f81e51a241a8abc5726e9ea2658f
Quelldatensatz
uspto-grants-1997_06
Patentnummer
US05639756

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