Methyl Ethyl Ketone → 4-[2-(Butan-2-ylidene)hydrazinyl]pyridin-2(1H)-one

HRID 1686019Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1686019
[NH:1]([C:3]1[CH:8]=[CH:7][NH:6][C:5](=[O:9])[CH:4]=1)[NH2:2].[CH3:10][C:11](=O)[CH2:12][CH3:13]>C(O)C>[C:11](=[N:2][NH:1][C:3]1[CH:8]=[CH:7][NH:6][C:5](=[O:9])[CH:4]=1)([CH2:12][CH3:13])[CH3:10]

Komponenten

4

Edukt 2

HCID 6569Methyl Ethyl KetoneHCID 136108294-Hydrazinylpyridin-2(1H)-one

Produkt 1

HCID 714120504-[2-(Butan-2-ylidene)hydrazinyl]pyridin-2(1H)-oneAusbeute 75 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Reaktionsbedingungen

Temperatur
0 °C

Versuchsvorschrift

4-hydrazino-1H-pyridin-2-one (20.1 g, 161.0 mmol) prepared in Step 1 and 2-butanone (21.6 ml, 241.0 mmol) were added to ethanol (400 ml). The reaction mixture was refluxed under stirring for 4 hours and cooled to 0° C. The resulting precipitate was filtered and then washed with cooled ethanol to give the titled compound as a white solid. (Yield: 75.0%)

Aufarbeitung

  1. temperatureThe reaction mixture was refluxed
  2. filtrationThe resulting precipitate was filtered
  3. washwashed with cooled ethanol

Quellen und Nachweise

ORD-Eintrag
ord-a6183902262e465cb02c104c445331a1
Quelldatensatz
uspto-grants-2012_04
Patentnummer
US08148529B2

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