Hydrochloric Acid → N-methyloxan-4-amine hydrochloride
Reaktionsgleichung
C([CH2:8][NH:9][CH:10]1[CH2:15][CH2:14][O:13][CH2:12][CH2:11]1)C1C=CC=CC=1.[ClH:16]>CO.CCOCC>[ClH:16].[CH3:8][NH:9][CH:10]1[CH2:15][CH2:14][O:13][CH2:12][CH2:11]1Komponenten
5
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 2
Versuchsvorschrift
The title compound was prepared according to Preparation 23 from benzylmethyl(tetrahydropyran-4-yl)amine (Preparation 87). Crude material was dissolved in methanol and a solution of 1M HCl in ether was added dropwise to form a precipitate. The product was filtered and washed with ether to give the title compound as the hydrochloride salt as a white crystalline solid. δH (CD3OD): 4.11-4.00 (2H, m), 3.53-3.43 (2H, m), 3.37-3.27 (1H, m), 2.74 (3H, s), 2.11-2.03 (2H, m), 1.74-1.60 (2H, m).
Aufarbeitung
- customThe title compound was prepared
- customto form a precipitate
- filtrationThe product was filtered
- washwashed with ether
Quellen und Nachweise
- ORD-Eintrag
- ord-3596797ec9cf4498a8f543bb2f4ededd
- Quelldatensatz
- uspto-grants-2012_04
- Patentnummer
- US08158622B2
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