2-(Methylamino)ethanol → Dodecyl(2-hydroxyethyl)methylamine

HRID 1700873Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1700873
I[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13].[CH3:14][NH:15][CH2:16][CH2:17][OH:18]>C(O)(C)C.CCOCC>[CH3:14][N:15]([CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13])[CH2:16][CH2:17][OH:18]

Komponenten

5

Edukt 2

HCID 80162-(Methylamino)ethanolHCID 202821-Iodododecane

Produkt 1

HCID 10657884Dodecyl(2-hydroxyethyl)methylamineAusbeute 97,5 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 3283Diethyl EtherLösungsmittelHCID 3776IsopropanolLösungsmittel

Versuchsvorschrift

A solution of iodododecane (18.1 g, 61.09 mmol) and 2-(methylamino)ethanol (23.0 g, 0.3 mol) in isopropanol (75 ml) was heated under reflux for 3 h. The cooled mixture was diluted with ether (500 ml), washed with water, brine and dried (magnesium sulfate). Evaporation of the solvent under reduced pressure and distillation of the residue under vacuum gave 14.5 g (97%) of N-methyl-N-dodecylethanolamine as a clear oil: b.p. 100-111° C./0.3 torr (bulb to bulb distillation, air bath temperature).

Aufarbeitung

  1. temperatureunder reflux for 3 h
  2. washwashed with water, brine
  3. dry with materialdried (magnesium sulfate)
  4. customEvaporation of the solvent
  5. distillationunder reduced pressure and distillation of the residue under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-46a099bcfddf4b5a8d8f95eada4da5b9
Quelldatensatz
uspto-grants-2002_02
Patentnummer
US06350892B1

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