tert.-butyl (4S)-1-n-butyl-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate → tert.-butyl (4S)-1-n-butyl-2-oxo-imidazolidine-4-carboxylate

HRID 1702209Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1702209
[CH2:1]([N:5]1[CH2:9][C@@H:8]([C:10]([O:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[O:11])[N:7](C(OCC2C=CC=CC=2)=O)[C:6]1=[O:27])[CH2:2][CH2:3][CH3:4]>[Pd].CO>[CH2:1]([N:5]1[CH2:9][C@@H:8]([C:10]([O:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[O:11])[NH:7][C:6]1=[O:27])[CH2:2][CH2:3][CH3:4]

Komponenten

4

Edukt 1

HCID 56608950tert.-butyl (4S)-1-n-butyl-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate

Produkt 1

HCID 86738844tert.-butyl (4S)-1-n-butyl-2-oxo-imidazolidine-4-carboxylateAusbeute 88,1 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

6.7 g of tert.-butyl (4S)-1-n-butyl-3-benzyloxycarbonyl-2-oxo-imidazolidine-4-carboxylate, 0.1 g of palladium-black and 200 ml of methanol are treated in the same manner as described in Example 1-(3). 3.8 g of tert.-butyl (4S)-1-n-butyl-2-oxo-imidazolidine-4-carboxylate are obtained as colorless syrup. Yield: 88.1%

Quellen und Nachweise

ORD-Eintrag
ord-bca6784ec2e346c2ae3eaeda8b3b0884
Quelldatensatz
uspto-grants-1983_04
Patentnummer
US04380644

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